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Table 4 Multivariate analysis of potential factors associated with overall survival in patients with locally advanced NSCLC

From: Systemic immune-inflammation index predicting chemoradiation resistance and poor outcome in patients with stage III non-small cell lung cancer

Variables

HR

95% CI

p

ECOG PS

  

0.008

 0–1

1.00

  

 2

1.744

1.158–2.626

 

T stage

  

0.028

 T1–T2

1.00

  

 T3–T4

1.332

1.032–1.718

 

N stage

  

0.018

 Negative

1.00

  

 Positive

1.848

1.113–3.068

 

Clinical stage

  

0.653

 III A

1.00

  

 III B

1.058

0.828–1.350

 

SII

  

< 0.001

 < 660

1.00

  

 ≥ 660

2.105

1.481–2.741

 

NLR

  

< 0.001

 < 3.57

1.00

  

 ≥ 3.57

1.934

1.448–2.585

 

PLR

  

0.083

 < 147

1.00

  

 ≥ 147

1.299

0.966–1.748

 

PNI

  

0.131

 ≥ 52.95

1.00

  

 < 52.95

1.263

0.933–1.709

 
  1. HR hazard ratio, 95 CI 95% confidence interval, SII systemic immune-inflammation index, NLR neutrophil/lymphocyte ratio, PLR platelet/lymphocyte ratio, PNI prognostic nutritional index