The effect of renal denervation in an experimental model of chronic renal insufficiency, The REmnant kidney Denervation In Pigs study (REDIP study)

Table 4 Laboratory Values at Follow up, n = 18 (denervated n = 13, control n = 5)

Variable	Group	Baseline Coef [95% CI]	Week 4 Coef [95% CI]	End of study Coef [95% CI]
Creatinine (μmol/l)	Control	119 [90–157]	140 [99–198]	283*^† [214–375]
Creatinine (μmol/l)	Denervation	111 [93–132]	125 [104–150]	267*^† [225–318]
Urea (mmol/l)	Control	2.97 [1.77–4.99]	3.40 [1.82–6.36]	7.53*^† [4.48–12.67]
Urea (mmol/l)	Denervation	3.05 [2.21–4.21]	3.31 [2.38–4.61]	8.30*^† [6.02–11.47]
Aldosteron (ng/l)	Control	3.20 [1.16–6.25]	4.82 [1.64–9.68]	5.00 [2.32–8.68]
Aldosteron (ng/l)	Denervation	6.53 [4.47–8.98]	4.64 [2.94–6.74]	2.13*^† [1.03–3.61]

Estimates are based on linear mixed models
Coef coefficient
* p < 0.05 vs. baseline
^†p < 0.05 vs. 4th week. No significant differences between groups were observed at any time point

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