Fig. 3
Chronic HBV infection affected the function of NK cells. MFI for CD69, PD1 and Tim-3 (a) on CD56+CD3− NK cells and the frequency of granzyme B+, perforin+ (b), IFN-γ+ and TNF-α+ (c) cells within CD56+CD3− NK cells in healthy controls (HC) and CHB patients (CHB)/CHB subgroups. Horizontal bars represent the median. HBV hepatitis B, CHB chronic hepatitis B, HC healthy control, IA immune active, IT immune tolerance, IC inactive CHB, and GZ grey zone