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TableĀ 4 Sensitivity, specificity and accuracy based on quantitative and qualitative FCIA assay

From: Flow cytometric immunobead assay for quantitative detection of platelet autoantibodies in immune thrombocytopenia patients

Autoantibody category Case (n) Sensitivity (%) Specificity (%) Accuracy (%)
Quantitative FCIA Qualitative FCIA Quantitative FCIA Qualitative FCIA Quantitative FCIA Qualitative FCIA
Anti-GPIX (%, n/n) 534 31.84 (64/201) 31.34 (63/201) 91.29 (304/333) 91.29 (304/333) 68.91 (368/534) 68.73 (367/534)
Anti-GPIb (%, n/n) 534 32.84 (66/201) 32.34 (65/201) 96.40 (321/333) 96.40 (321/333) 72.47 (387/534) 72.28 (386/534)
Anti-GPIIIa (%, n/n) 534 32.84 (66/201) 27.86 (56/201) 95.20 (317/333) 97.30 (324/333) 71.72(383/534) 71.16 (380/534)
Anti-GPIIb (%, n/n) 534 30.35 (61/201) 25.87 (52/201) 95.80 (319/333) 97.30 (324/333) 71.16 (380/534) 70.41 (376/534)
Anti-P-selectin (%, n/n) 534 40.30 (81/201) 39.80 (80/201) 95.80 (319/333) 96.10 (320/333) 74.91 (400/534) 74.91 (400/534)
5 antibody combined (%, n/n) 534 73.13 (147/201) 73.13 (147/201) 81.98 (273/333) 82.88 (276/333) 78.65 (420/534) 79.21 (423/534)
  1. FCIA flow cytometric immunobead assay