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Table 1 Subjects characteristics

From: Flow cytometric immunobead assay for quantitative detection of platelet autoantibodies in immune thrombocytopenia patients

Characteristics

Test set 1

Test set 2

Pilot set

ITP (n = 201)

Non-ITP (n = 126)

HC (n = 207)

ITP (n = 41)

Non-ITP (n = 37)

HC (n = 36)

ITP (n = 8)

Disease subtype (n)

Newly-diagnosed (63)

Persistent (60)

Chronic (78)

NA

NA

NA

NA

NA

Newly-diagnosed (8)

Gender (female/male, n)

45/18

38/22

48/30

56/70

76/131

24/17

11/26

13/23

5/3

Age (median, range, years)

53 (18, 86)

53 (9, 86)

54 (13, 83)

44 (13, 88)

48 (24, 91)

33 (5, 68)

42 (9, 64)

30 (21, 50)

38.5 (9, 69)

Platelet count (× 109/L)a

29.0 ± 16.9

41.0 ± 20.0

42.4 ± 20.3

41.5 ± 21.8

216.1 ± 56.8

38.2 ± 32.3

42.2 ± 31.0

211.4 ± 32.4

17.8 ± 9.9

Treatment (n, %)b

NA

58 (96.7)

78 (100)

NA

NA

27 (65.9)

NA

NA

NA

Steroids

NA

51 (85.0)

75 (96.2)

NA

NA

27 (65.9)

NA

NA

NA

Immunosuppressants

NA

15 (25.0)

27 (34.6)

NA

NA

10 (24.4)

NA

NA

NA

Splenectomy

NA

0 (0)

3 (3.8)

NA

NA

0 (0)

NA

NA

NA

Others

NA

10 (16.7)

23 (29.5)

NA

NA

5 (12.2)

NA

NA

NA

  1. Data are presented as mean ± SD, or percentage in parenthesis
  2. Steroids included dexathemethasone, prednisone or methylprednisolone; immunosuppressants included Cyclosporine A (CSA), Azathioprine (Aza) or Vindesine (VDS); others included Intravenous Immunoglobulin (IVIg), thrombopoietin (TPO) and Rituximab
  3. HC healthy controls, NA not applicable or not available
  4. a Platelet count at first visit
  5. bAll the included patients did not receive any medical treatment for at least 1 month before sampling