Fig. 1

A schematic diagram of the perfusion circuit. The blood based perfusate circulates from the venous reservoir into the centrifugal pump. It is pumped into the membrane oxygenator at a set pump speed and mean arterial pressure were it is oxygenated and warmed to 37.4 °C before entering into the arterial arm of the circuit and into the kidney via the renal artery. The Cytosorb was attached to a line from the oxygenator then fed back into the venous reservoir allowing a collateral circulation of the perfusate without altering the renal blood flow