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Table 3 Stratified analysis of the association between red cell distribution width and all-cause mortality

From: Association of red cell distribution width with all-cause and cardiovascular-specific mortality in African American and white adults: a prospective cohort study

RDWa HRb (95% CI) HRb (95% CI) P-interactionc
Sex Men Women  
 RDW-Q1 1.00 1.00 0.42
 RDW-Q2 1.39 (0.73–2.67) 0.71 (0.34–1.47)  
 RDW-Q3 1.20 (0.60–2.38) 0.85 (0.42–1.7)  
 RDW-Q4 2.41 (1.26–4.59) 1.17 (0.6–2.28)  
 P-trendd 0.006 0.29  
Race African Americans Whites  
 RDW-Q1 1.00 1.00 0.35
 RDW-Q2 0.76 (0.4–1.44) 1.68 (0.79–3.59)  
 RDW-Q3 0.86 (0.46–1.58) 1.57 (0.71–3.49)  
 RDW-Q4 1.18 (0.66–2.1) 3.60 (1.68–7.72)  
 P-trendd 0.22 0.001  
Poverty status Above Below  
 RDW-Q1 1.00 1.00 0.17
 RDW-Q2 1.62 (0.76–3.49) 0.85 (0.45–1.61)  
 RDW-Q3 2.17 (1.03–4.56) 0.63 (0.32–1.24)  
 RDW-Q4 2.80 (1.33–5.92) 1.33 (0.74–2.4)  
 P-trendd 0.005 0.18  
Current smoking No Yes  
 RDW-Q1 1.00 1.00 0.42
 RDW-Q2 1.31 (0.61–2.81) 1.04 (0.56–1.94)  
 RDW-Q3 0.82 (0.34–1.99) 1.28 (0.71–2.31)  
 RDW-Q4 1.83 (0.82–4.06) 1.82 (1.03–3.23)  
 P-trendd 0.17 0.01  
BMI BMI < 25.0 BMI ≥ 25.0  
 RDW-Q1 1.00 1.00 0.004
 RDW-Q2 1.16 (0.59–2.28) 0.89 (0.44–1.8)  
 RDW-Q3 0.79 (0.37–1.69) 1.34 (0.7–2.55)  
 RDW-Q4 1.44 (0.7–2.95) 2.06 (1.11–3.83)  
 P-trendd 0.39 0.002  
  1. BMI body mass index, CI confidence intervals, HR hazard ratio
  2. aRDW, red cell distribution width levels in quartiles. Quartile cut-off points were 13.2, 13.8, and 14.6%
  3. bMultivariable adjusted Cox proportional hazards regression model
  4. cp-value from likelihood ratio test of interaction
  5. dLinear trend test was performed using median of the quartile as a continuous variable in the Cox proportional hazards regression model