|
RDWa
|
HRb (95% CI)
|
HRb (95% CI)
|
P-interactionc
|
|---|
|
Sex
|
Men
|
Women
| |
|
RDW-Q1
|
1.00
|
1.00
|
0.42
|
|
RDW-Q2
|
1.39 (0.73–2.67)
|
0.71 (0.34–1.47)
| |
|
RDW-Q3
|
1.20 (0.60–2.38)
|
0.85 (0.42–1.7)
| |
|
RDW-Q4
|
2.41 (1.26–4.59)
|
1.17 (0.6–2.28)
| |
|
P-trendd
|
0.006
|
0.29
| |
|
Race
|
African Americans
|
Whites
| |
|
RDW-Q1
|
1.00
|
1.00
|
0.35
|
|
RDW-Q2
|
0.76 (0.4–1.44)
|
1.68 (0.79–3.59)
| |
|
RDW-Q3
|
0.86 (0.46–1.58)
|
1.57 (0.71–3.49)
| |
|
RDW-Q4
|
1.18 (0.66–2.1)
|
3.60 (1.68–7.72)
| |
|
P-trendd
|
0.22
|
0.001
| |
|
Poverty status
|
Above
|
Below
| |
|
RDW-Q1
|
1.00
|
1.00
|
0.17
|
|
RDW-Q2
|
1.62 (0.76–3.49)
|
0.85 (0.45–1.61)
| |
|
RDW-Q3
|
2.17 (1.03–4.56)
|
0.63 (0.32–1.24)
| |
|
RDW-Q4
|
2.80 (1.33–5.92)
|
1.33 (0.74–2.4)
| |
|
P-trendd
|
0.005
|
0.18
| |
|
Current smoking
|
No
|
Yes
| |
|
RDW-Q1
|
1.00
|
1.00
|
0.42
|
|
RDW-Q2
|
1.31 (0.61–2.81)
|
1.04 (0.56–1.94)
| |
|
RDW-Q3
|
0.82 (0.34–1.99)
|
1.28 (0.71–2.31)
| |
|
RDW-Q4
|
1.83 (0.82–4.06)
|
1.82 (1.03–3.23)
| |
|
P-trendd
|
0.17
|
0.01
| |
|
BMI
|
BMI < 25.0
|
BMI ≥ 25.0
| |
|
RDW-Q1
|
1.00
|
1.00
|
0.004
|
|
RDW-Q2
|
1.16 (0.59–2.28)
|
0.89 (0.44–1.8)
| |
|
RDW-Q3
|
0.79 (0.37–1.69)
|
1.34 (0.7–2.55)
| |
|
RDW-Q4
|
1.44 (0.7–2.95)
|
2.06 (1.11–3.83)
| |
|
P-trendd
|
0.39
|
0.002
| |
-
BMI body mass index, CI confidence intervals, HR hazard ratio
-
aRDW, red cell distribution width levels in quartiles. Quartile cut-off points were 13.2, 13.8, and 14.6%
-
bMultivariable adjusted Cox proportional hazards regression model
-
cp-value from likelihood ratio test of interaction
-
dLinear trend test was performed using median of the quartile as a continuous variable in the Cox proportional hazards regression model
