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Table 2 Risk of all-cause and cardiovascular disease-specific mortality and red cell distribution width

From: Association of red cell distribution width with all-cause and cardiovascular-specific mortality in African American and white adults: a prospective cohort study

RDWa

Total

Events

HRb (95% CI)

HRc (95% CI)

HRd (95% CI)

All-cause mortality

 RDW-Q1

638

41

1.00

1.00

1.00

 RDW-Q2

743

56

1.19 (0.79–1.78)

1.17 (0.78–1.76)

1.06 (0.66–1.72)

 RDW-Q3

647

50

1.12 (0.74–1.7)

1.13 (0.74–1.71)

1.08 (0.67–1.75)

 RDW-Q4

676

79

1.90 (1.30–2.78)

1.95 (1.32–2.88)

1.73 (1.10–2.74)

 P-trende

  

< 0.001

< 0.001

0.006

CVD-specific mortality

 RDW-Q1

605

8

1.00

1.00

1.00

 RDW-Q2

702

15

1.60 (0.68–3.78)

1.55 (0.65–3.67)

0.92 (0.34–2.49)

 RDW-Q3

613

16

1.79 (0.77–4.18)

1.73 (0.73–4.09)

1.09 (0.41–2.85)

 RDW-Q4

630

33

4.03 (1.86–8.74)

3.89 (1.75–8.62)

2.49 (1.03–6.05)

 P-trende

  

< 0.001

< 0.001

0.004

  1. CI confidence interval, CVD cardiovascular diseases, HR hazard ratio
  2. aRDW, red-cell distribution level in quartiles. Quartile cut-off points were 13.2, 13.8, and 14.6%
  3. bUnadjusted Cox proportional hazards regression model
  4. cAdjusted for age, sex, race, and poverty status
  5. dAdjusted for age, sex, race, poverty status, smoking status, body mass index, low density lipoprotein cholesterol, diagnosis of hypertension, and diagnosis of diabetes mellitus
  6. eLinear trend test was performed using median of the quartile as a continuous variable in the Cox proportional hazards regression model