Fig. 7
From: A novel small molecule inhibitor of p32 mitochondrial protein overexpressed in glioma
M36 promotes an increase in lactate production resulting in media acidification. a Culture media acidification for SF188 glioma cells and patient-derived GBM8 cells treated with 50 µM M36 for 4 and 7 days, respectively. b Lactate levels within the culture media were determined and relative lactate levels are shown after normalizing for cell number. The affect of M36 on cell proliferation is shown as relative cell viability (%). Bars represent mean ± standard deviation for 3 independent experiments (***p < 0.001)