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Fig. 7 | Journal of Translational Medicine

Fig. 7

From: Porcine model of progressive cardiac hypertrophy and fibrosis with secondary postcapillary pulmonary hypertension

Fig. 7

Serial measurements of plasma NGAL and proBNP levels. a Rapid increase in NGAL was detected already 2 months after creation of artificial aortic isthmus stenosis, even when the transstenotic gradient was not yet significant. b Late elevation of proBNP in the plasma was observed, indicating a compensatory mechanism of aortic stenosis and developing heart failure. Results are expressed as mean ± SD, *p < 0.05 (ANOVA) between the groups at the same time points (n = 7, HYPI, n = 5, control)

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