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Fig. 4 | Journal of Translational Medicine

Fig. 4

From: Porcine model of progressive cardiac hypertrophy and fibrosis with secondary postcapillary pulmonary hypertension

Fig. 4

Imaging of aortic isthmus stenosis and development of myocardial hypertrophy. ad Intraluminal echocardiography proximal to stent (a), in stent (b) and distal to stent (c) in the descending aorta 5 months after percutaneous stent implantation showing narrowing of the aorta in the stent level with tissue proliferation between the stent and the growing aorta in juvenile pigs (b). d Pulsatile Doppler measurements of the transstenotic gradient. e M-mode echocardiography displays concentric hypertrophy 5 month after creation of artificial aortic isthmus stenosis (lower panel) as compared to normal (upper panel). f Long axis cardiac magnetic resonance imaging confirms the severe concentric hypertrophy in HYPI pigs (right panel) in contrast with normal left ventricular myocardium of a control pig (left panel)

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