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Fig. 3 | Journal of Translational Medicine

Fig. 3

From: Porcine model of progressive cardiac hypertrophy and fibrosis with secondary postcapillary pulmonary hypertension

Fig. 3

Creation of artificial aortic isthmus stenosis and myocardial hypertrophy in pigs via percutaneous stent implantation in the descending aorta. a Contrast angiography in a farm pig (15 kg) immediately after implantation of a bare metal stent (0.9 mm diameter, 20 mm length). b Computed tomographic (CT) aortography shows the location of the stent in anteroposterior view immediately after implantation. c Contrast-enhanced CT (lateral view) after stent implantation. d Magnetic resonance imaging (MRI) 5 months after stenting of the descending aorta displays the stent (red arrow), the pre- and poststenotic dilation (yellow arrows). Anteroposterior view. e Contrast enhanced MRI at 5-month follow-up shows the severely limited flow (yellow arrow) through the stent (red arrow). Lateral view. f Systolic frame from phase-contrast MRI cines; Aorta thoracalis, diameter: 15 mm, stent diameter: 9 mm, aliasing signal-fast moving blood in the stent area. (Maximum velocity 300 m/s equivalent with 56 mmHg pressure gradient on trough–plane images); 5-month follow-up

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