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Table 3 Reduced glutathione (GSH), oxidized glutathione (GSSG), GSH/GSSG ratio, and MDA in healthy volunteers and diabetic subjects

From: Altered Semmes–Weinstein monofilament test results are associated with oxidative stress markers in type 2 diabetic subjects

  Healthy volunteers (n = 55) T2DM with altered SWM test (n = 34) T2DM without altered SWM test (n = 36)
GSH (nmol/ml) 22.53 ± 3.82** 19.81 ± 4.45 19.50 ± 4.36
GSSG (nmol/ml) 2.78 ± 1.28** 3.53 ± 0.31* 3.3 ± 0.35
GSH/GSSG ratio 10.1 ± 5.29** 5.67 ± 1.43 5.96 ± 1.41
MDA (nmol/ml) 1.37 ± 0.23** 1.88 ± 0.16* 1.75 ± 0.19
  1. All values are indicated as mean ± standard deviation
  2. T2DM type 2 diabetic subjects, MDA malonildialdehyde, GSH reduced glutathione, GSSG oxidized glutathione, oxidized-LDL oxidized low-density lipoprotein, SWM Semmes-Weinstein monofilament test
  3. * p < 0.05 T2DM subjects with altered SWM test vs T2DM subjects without altered SWM test
  4. ** p < 0.05 healthy volunteers vs T2DM subjetcs