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Table 2 EPC marker

From: Multiple therapeutic effect of endothelial progenitor cell regulated by drugs in diabetes and diabetes related disorder

Type of EPC Marker References
Peripheral blood circulating EPC vWF, CD31, CD34, VEGF-R2, CD105, CD146 Untergasser et al. [21]
Peripheral blood circulating EPC CD34+/CD133+/VEGF-R2+ Capiod et al. [22]
Peripheral blood circulating EPC CD133−, CD34+, VEGFR-2, VE-cadherin, eNOS, vWF Hristov, Weber [23]
Peripheral blood circulating EPC Positive for acetylated LDL, vWF, P1H12, thrombomodulin, flk-1, VE-cadherin, PECAM-1, CD34, CD14- Lin et al. [24]
Peripheral blood circulating EPC CD31, Tie-2, and Flk-1, VEGFR-2 Ito et al. [25]; Hill et al. [66]
Bone marrow derived EPC CD31(+), c-Kit(+), Sca-1(+), Lin(−) Khoo et al. [26]
Bone marrow derived EPC VEGFR-2, CD31, VE-cadherin, vWF Hristov et al. [27]
Bone marrow derived EPC Flk1(+)CD31(−)CD34(−) Guo et al. [28]
Bone marrow derived EPC KDR, vWF, eNOS, VE-cadherin, CD146, uptake of DiI-acetylated LDL and binding of lectin Yoon et al. [29]
Bone marrow derived EPC Flk-1, Tie-2, Sca-1, and CD34 Asahara et al. [56]
Embryo derived EPC Early: Flk-1, PECAM, and tie-2, VEGF; mature: tie-I, MECA-32 antigen, VE-cadherin, and MEC-14.7 Vittet et al. [30]
Embryo derived EPC BS Lectin, vWF, DiI Ac-LDL Doetschman et al. [31]
Embryo derived EPC CD31, CD34, Flk-1, VE-cadherin, and vWF, uptake of DiI-ac-LDL Li et al. [32]
Embryo derived EPC eNOS, VEGF Flk-1 and Flt-1, VE-cadherin, CD34, PECAM-1 McCloskey et al. [33]; Glaser et al. [34]
Cord blood EPC UEA Lectin Binding, VEGF receptor-2, vWF, CD31, CD34, eNOS, Ac-LDL-uptake Schmidt et al. [35]
Cord blood EPC DiI ac-LDL, KDR, VE-cadherin, CD31, vWF, CD45− Murohara et al. [36]
Cord blood EPC VEGFR-2, KDR, VE Cadherin (CD144), CD18, and CD61, acetylated LDL uptake and ulex lectin binding Ahrens et al. [37]
Cord blood EPC Positive: CD31, VE-cadherin, and vWF Negative: CD45, CD90, α-SMA Lin et al. [38]
Cord blood EPC Flt-1/VEGFR-1, ecNOS, VE-cadherin, von Willebrand factor, and secreted VEGF Jang et al. [39]
HUVEC derived EPC vWF, CD31, CD34, UEA-1 lectin Hughes et al. [40]
HUVEC derived EPC CD133, P1H12, VEGFR2, PECAM, and endoglin, ICAM1 Bagley et al. [41]
HUVEC derived EPC Ac LDL, VEGFR1, VEGFR2, FLT-1 and KDR Carvalho et al. [42]