Table 3 CR rate of different gene mutation and expression group in intermediate risk group
Gene mutation | CR no (%) | Gene expression | CR no (%) |
|---|---|---|---|
FLT3 ITD/TKD | MECOM | ||
 Mutated | 60 (59.4) |  Low | 160 (74.4) |
 Not mutated | 212 (70.7) |  High | 101 (58.0) |
 P | 0.036 |  P | 0.001 |
NRAS | MEIS1 | ||
 Mutated | 25 (78.1) |  Low | 138 (75.8) |
 Not mutated | 247 (66.9) |  High | 134 (61.2) |
 P | 0.194 |  P | 0.002 |
C-KIT (NAÂ =Â 2) | SPI1 | ||
 Mutated | 19 (79.2) |  Low | 158 (72.5) |
 Not mutated | 271 (67.9) |  High | 114 (62.3) |
 P | 0.223 |  P | 0.030 |
DNMT3A | ERG | ||
 Mutated | 33 (61.1) |  Low | 151 (70.6) |
 Not mutated | 239 (68.9) |  High | 121 (64.7) |
 P | 0.256 |  P | 0.211 |
IDH1 (NAÂ =Â 1) | WT1 | ||
 Mutated | 23 (60.5) |  Low | 136 (70.5) |
 Not mutated | 249 (68.6) |  High | 136 (66.0) |
 P | 0.311 |  P | 0.341 |
IDH2 | GATA2 | ||
 Mutated | 22 (62.9) |  Low | 128 (67.7) |
 Not mutated | 250 (68.3) |  High | 144 (67.9) |
 P | 0.510 |  P | 0.966 |
NPM1/DNMT3A | BAALC | ||
 NPM1-mut/DNMT3A-wt | 48 (78.7) |  Low | 159 (69.7) |
 Others | 224 (65.9) |  High | 113 (65.3) |
 P | 0.049 |  P | 0.348 |
WT1 | Â | Â | |
 Mutated | 26 (76.5) |  |  |
 Not mutated | 245 (66.9) |  |  |
 P | 0.255 |  |  |
CEBPA | Â | Â | |
 Biallelic mutated | 59 (83.1) |  |  |
 Monoallelic mutated | 21 (61.8) |  |  |
 Not mutated | 189 (64.7) |  |  |
 P | 0.009 |  |  |
MLL-PTD | Â | Â | |
 Mutated | 14 (60.9) |  |  |
 Not mutated | 258 (68.3) |  |  |
 P | 0.462 |  |  |