Fig. 3

XICs of SPOP WT peptides in mutant region detected in HEK293T cell lines expressing WT SPOP cell line (a) and their corresponding mutant counterparts detected in SPOP Y87N, F102C and F133V mutant cell lines (b) using PRISM-SRM (AA shown in red font indicates mutation site). XICs for all the peptide candidates (details available in Additional file 4: Table S2) in four SPOP cell lines were shown in Additional file 9: Figure S7