Table 2 Correlation between IQGAP3 expression and clinicopathologic characteristics of HCC
From: Role of IQGAP3 in metastasis and epithelial–mesenchymal transition in human hepatocellular carcinoma
Clinical character | Variable | Total | IQGAP3 | Chi square test, P value | Fisher’s exact test, P value | |
|---|---|---|---|---|---|---|
Low-expression, no. cases % | High-expression, no. cases % | |||||
Age (years) | ≤50 | 53 | 31 (25.8) | 22 (18.3) | 0.720 | 0.853 |
>50 | 67 | 37 (30.8) | 30 (25.0) | |||
Gender | Female | 13 | 5 (4.2) | 8 (6.7) | 0.161 | 0.236 |
Male | 107 | 63 (52.5) | 44 (36.7) | |||
Clinical stage | I | 48 | 31 (25.8) | 17 (14.2) | 0.001 | |
II | 44 | 31 (25.8) | 13 (10.8) | |||
III | 21 | 6 (5.0) | 15 (12.5) | |||
IV | 7 | 0 (0.0) | 7 (5.8) | |||
Cirrhosis | No | 58 | 32 (26.7) | 26 (21.7) | 0.749 | 0.854 |
Yes | 62 | 36 (30.0) | 26 (21.7) | |||
T classification | T1 | 53 | 27 (22.5) | 26 (21.7) | 0.460 | |
T2 | 12 | 7 (5.8) | 5 (4.2) | |||
T3 | 6 | 5 (4.2) | 1 (0.8) | |||
T4 | 49 | 29 (24.2) | 20 (16.7) | |||
N classification | N0 | 97 | 62 (51.7) | 35 (29.2) | 0.001 | 0.002 |
N1 | 23 | 6 (5.0) | 17 (14.2) | |||
M classification | M0 | 113 | 68 (56.7) | 45 (37.5) | 0.002 | 0.002 |
M1 | 7 | 0 (0.0) | 7 (5.8) | |||
HCV | No | 119 | 67 (55.8) | 52 (43.3) | 0.380 | 1.000 |
Yes | 1 | 1 (0.8) | 0 (0.0) | |||
HBsAg | Negative | 17 | 8 (6.7) | 9 (7.5) | 0.388 | 0.436 |
Positive | 103 | 60 (50.0) | 43 (35.8) | |||
Vital status | Alive | 17 | 15 (12.5) | 2 (1.7) | 0.005 | 0.007 |
Death | 103 | 53 (44.2) | 50 (41.7) | |||