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Fig. 1 | Journal of Translational Medicine

Fig. 1

From: Temperature variability in the day–night cycle is associated with further intracranial pressure during therapeutic hypothermia

Fig. 1

Temperature variability (TV) correlates inversely with mean intracranial pressure in the following day (ICP24) during hypothermia. Upper left-hand graph displays the distribution of the ICP24 in function of the TV from which derived the regression line and the formulas displayed above the graph. Upper right-hand graph displays daily TV and ICP24 of patients 1–3. Note that patient #2 underwent hypothermia during day 6 of monitoring. Broadly, the inverse of TV parallels ICP24. The remaining boxes display the daily temperature curves in degrees Celsius and the corresponding ICP curves in the following day. Temperature was recorded at 10 Hz and ICP at 1 Hz. Vertical line in the temperature curves corresponds to 18 h and divide the graph in day at left and night at right. Horizontal line in the ICP curves sets 20 mmHg. These graphs allow a qualitative analysis regarding temperature variability during day and night and ICP in the next 24 h. For example, compare the variability between day and night of days 6 and 8 of monitoring of patient #1 and the respective ICP values in the next day. CI confidence interval, D day of monitoring, PI prediction interval, arrows sudden ICP decrease due to cerebrospinal fluid drainage

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