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Table 1 Clinicopathologic features of 334 CRC patients

From: Comparative analysis of the EGFR, HER2, c-MYC, and MET variations in colorectal cancer determined by three different measures: gene copy number gain, amplification status and the 2013 ASCO/CAP guideline criterion for HER2 testing of breast cancer

Characteristic

Examined no. (%)

Age (years)

 Mean ± SD

64.04 ± 11.57

 Range

20–95

Tumor size (cm)

 Mean ± SD

5.32 ± 2.21

 Range

1.0–13.0

Sex

 Male

185 (55.4)

 Female

149 (44.6)

Location

 Right

93 (27.8)

 Left

127 (38.0)

 Rectum

114 (34.1)

Histologic grade

 Low grade

303 (90.7)

 High grade

31 (9.3)

Tumor border

 Expanding

49 (14.7%)

 Infiltrative

285 (85.3%)

Lymphatic invasion

 Absent

143 (42.8%)

 Present

191 (57.2%)

Venous invasion

 Absent

272 (81.4%)

 Present

62 (18.6%)

Neural invasion

 Absent

231 (69.2%)

 Present

103 (30.8%)

pTNM stage

 I–III

273 (81.7)

 IV

61 (18.3)

MSI status (n = 323)

 MSS/MSI-L

296 (91.6)

 MSI-H

27 (8.4)

  1. SD standard deviation, MSI microsatellite instability, MSS microsatellite instability stable, MSI-L microsatellite instability-low, MSI-H microsatellite instability-high