Skip to main content

Table 2 The list of proteins significant elevated in induced sputum of asthmatic patients as compared with controls (data were showed as fold change of the controls)

From: Proteomic analysis of sputum reveals novel biomarkers for various presentations of asthma

 

Biological process or molecular function

CA

CVA

CTVA

Correlation with eosinophils

r

P

A2M

Protease inhibitor

2.1

1.9

1.7

0.0542

0.5614

ANXA1

Adaptive immunity, immunity, inflammatory response

1.4

2.3

1.7

−0.0775

0.4063

APOA2

Host-virus interaction, lipid transport, transport

2.3

2.7

2.3

0.0370

0.6918

ELANE

Hydrolase, protease, serine protease

1.6

1.5

1.6

0.1145

0.2191

GPI

Angiogenesis, gluconeogenesis, glycolysis

1.7

1.7

1.4

0.2537

0.0058

S100A8

Apoptosis, autophagy, chemotaxis, immunity, inflammatory

3.5

3.4

2.3

0.1505

0.1053

S100A9

Apoptosis, autophagy, chemotaxis, immunity, inflammatory

3.0

3.1

2.1

0.1768

0.0565

S100A12

Immunity, inflammatory response, innate immunity

1.9

2.0

1.6

0.2929

0.0014

AGT

Vasoactive, vasoconstrictor

1.4

NS

NS

0.0971

0.2979

C5

Complement pathway, cytolysis, immunity, inflammatory

2.1

NS

NS

−0.0420

0.6526

FGA

Blood coagulation, hemostasis, immunity

1.9

NS

NS

0.0289

0.7573

SERPINF2

Serine protease inhibitor

2.6

NS

NS

  

APOA1

Metabolism, transport

1.7

1.6

NS

0.0495

0.5960

CHI3L1

Apoptosis, inflammatory response

4.4

3.4

NS

−0.0058

0.9497

FGB

Blood coagulation, hemostasis, immunity

1.7

1.8

NS

0.0529

0.5709

HPX

Host-virus interaction, transport

1.6

1.3

NS

0.1797

0.0525

ITIH4

Inflammatory responses to trauma

2.5

1.9

NS

−0.0187

0.8416

ORM1

Transport protein in the blood stream

1.4

1.4

NS

0.1806

0.0514

IL1RN

Immune response

NS

3.1

NS

0.1631

0.0789

PRG2

Hydrolase

2.0

NS

7.0

−0.0388

0.6777

B2M

Immunity

NS

NS

1.6

0.0976

0.2994

CTSB

Hydrolase, protease, thiol protease

NS

NS

1.4

0.0662

0.4786

FN1

Acute phase, angiogenesis, cell adhesion, cell shape

NS

NS

1.6

0.0487

0.6021

  1. NS not significant