Skip to main content

Advertisement

Springer Nature is making SARS-CoV-2 and COVID-19 research free. View research | View latest news | Sign up for updates

Table 2 The list of proteins significant elevated in induced sputum of asthmatic patients as compared with controls (data were showed as fold change of the controls)

From: Proteomic analysis of sputum reveals novel biomarkers for various presentations of asthma

  Biological process or molecular function CA CVA CTVA Correlation with eosinophils
r P
A2M Protease inhibitor 2.1 1.9 1.7 0.0542 0.5614
ANXA1 Adaptive immunity, immunity, inflammatory response 1.4 2.3 1.7 −0.0775 0.4063
APOA2 Host-virus interaction, lipid transport, transport 2.3 2.7 2.3 0.0370 0.6918
ELANE Hydrolase, protease, serine protease 1.6 1.5 1.6 0.1145 0.2191
GPI Angiogenesis, gluconeogenesis, glycolysis 1.7 1.7 1.4 0.2537 0.0058
S100A8 Apoptosis, autophagy, chemotaxis, immunity, inflammatory 3.5 3.4 2.3 0.1505 0.1053
S100A9 Apoptosis, autophagy, chemotaxis, immunity, inflammatory 3.0 3.1 2.1 0.1768 0.0565
S100A12 Immunity, inflammatory response, innate immunity 1.9 2.0 1.6 0.2929 0.0014
AGT Vasoactive, vasoconstrictor 1.4 NS NS 0.0971 0.2979
C5 Complement pathway, cytolysis, immunity, inflammatory 2.1 NS NS −0.0420 0.6526
FGA Blood coagulation, hemostasis, immunity 1.9 NS NS 0.0289 0.7573
SERPINF2 Serine protease inhibitor 2.6 NS NS   
APOA1 Metabolism, transport 1.7 1.6 NS 0.0495 0.5960
CHI3L1 Apoptosis, inflammatory response 4.4 3.4 NS −0.0058 0.9497
FGB Blood coagulation, hemostasis, immunity 1.7 1.8 NS 0.0529 0.5709
HPX Host-virus interaction, transport 1.6 1.3 NS 0.1797 0.0525
ITIH4 Inflammatory responses to trauma 2.5 1.9 NS −0.0187 0.8416
ORM1 Transport protein in the blood stream 1.4 1.4 NS 0.1806 0.0514
IL1RN Immune response NS 3.1 NS 0.1631 0.0789
PRG2 Hydrolase 2.0 NS 7.0 −0.0388 0.6777
B2M Immunity NS NS 1.6 0.0976 0.2994
CTSB Hydrolase, protease, thiol protease NS NS 1.4 0.0662 0.4786
FN1 Acute phase, angiogenesis, cell adhesion, cell shape NS NS 1.6 0.0487 0.6021
  1. NS not significant