From: Proteomic analysis of sputum reveals novel biomarkers for various presentations of asthma
 | Biological process or molecular function | CA | CVA | CTVA | Correlation with eosinophils | |
---|---|---|---|---|---|---|
r | P | |||||
A2M | Protease inhibitor | 2.1 | 1.9 | 1.7 | 0.0542 | 0.5614 |
ANXA1 | Adaptive immunity, immunity, inflammatory response | 1.4 | 2.3 | 1.7 | −0.0775 | 0.4063 |
APOA2 | Host-virus interaction, lipid transport, transport | 2.3 | 2.7 | 2.3 | 0.0370 | 0.6918 |
ELANE | Hydrolase, protease, serine protease | 1.6 | 1.5 | 1.6 | 0.1145 | 0.2191 |
GPI | Angiogenesis, gluconeogenesis, glycolysis | 1.7 | 1.7 | 1.4 | 0.2537 | 0.0058 |
S100A8 | Apoptosis, autophagy, chemotaxis, immunity, inflammatory | 3.5 | 3.4 | 2.3 | 0.1505 | 0.1053 |
S100A9 | Apoptosis, autophagy, chemotaxis, immunity, inflammatory | 3.0 | 3.1 | 2.1 | 0.1768 | 0.0565 |
S100A12 | Immunity, inflammatory response, innate immunity | 1.9 | 2.0 | 1.6 | 0.2929 | 0.0014 |
AGT | Vasoactive, vasoconstrictor | 1.4 | NS | NS | 0.0971 | 0.2979 |
C5 | Complement pathway, cytolysis, immunity, inflammatory | 2.1 | NS | NS | −0.0420 | 0.6526 |
FGA | Blood coagulation, hemostasis, immunity | 1.9 | NS | NS | 0.0289 | 0.7573 |
SERPINF2 | Serine protease inhibitor | 2.6 | NS | NS | Â | Â |
APOA1 | Metabolism, transport | 1.7 | 1.6 | NS | 0.0495 | 0.5960 |
CHI3L1 | Apoptosis, inflammatory response | 4.4 | 3.4 | NS | −0.0058 | 0.9497 |
FGB | Blood coagulation, hemostasis, immunity | 1.7 | 1.8 | NS | 0.0529 | 0.5709 |
HPX | Host-virus interaction, transport | 1.6 | 1.3 | NS | 0.1797 | 0.0525 |
ITIH4 | Inflammatory responses to trauma | 2.5 | 1.9 | NS | −0.0187 | 0.8416 |
ORM1 | Transport protein in the blood stream | 1.4 | 1.4 | NS | 0.1806 | 0.0514 |
IL1RN | Immune response | NS | 3.1 | NS | 0.1631 | 0.0789 |
PRG2 | Hydrolase | 2.0 | NS | 7.0 | −0.0388 | 0.6777 |
B2M | Immunity | NS | NS | 1.6 | 0.0976 | 0.2994 |
CTSB | Hydrolase, protease, thiol protease | NS | NS | 1.4 | 0.0662 | 0.4786 |
FN1 | Acute phase, angiogenesis, cell adhesion, cell shape | NS | NS | 1.6 | 0.0487 | 0.6021 |