Skip to main content

Advertisement

Springer Nature is making SARS-CoV-2 and COVID-19 research free. View research | View latest news | Sign up for updates

Table 1 Demographic and clinical features of included subjects

From: Proteomic analysis of sputum reveals novel biomarkers for various presentations of asthma

  Healthy controls Patients with asthma P Controls vs. Patients P CA vs. CVA vs. CVTA
Total CA CVA CTVA
No. of patients 30 87 30 27 30   
Age, years 44.0 ± 12.8 42.1 ± 13.8 41.4 ± 13.6 45.0 ± 13.2 40.1 ± 14.4 0.501 0.399
Male sex, no. (%) 15 (50) 42 (48) 14 (47) 10 (37) 18 (60) 0.871 0.218
Smoking status
 Smokers, no. (%) 9 (30) 13 (17) 3 (10) 4 (15) 6 (20) 0.069 0.554
 Pack/years 33.1 ± 42.0 20.5 ± 18.9 21.6 ± 25.0 22.5 ± 20.6 21.5 ± 17.4 0.322 0.997
History of atopy, no. (%) 6 (20) 30 (34) 13 (43) 10 (37) 7 (23) 0.138 0.250
BMI, kg/m2 24.3 ± 3.7 23.2 ± 2.8 23.6 ± 2.4 23.7 ± 2.8 22.5 ± 3.1 0.085 0.187
Serum IgE, IU/mL 1.5 ± 0.6 1.9 ± 0.7 1.9 ± 0.8 1.8 ± 0.8 2.0 ± 0.6 0.014 0.668
FEV1, %Predicted 99.1 ± 13.5 85.9 ± 16.1 80.7 ± 14.6 90.5 ± 17.6 87.1 ± 15.0 <0.001 0.062
FEV1/FVC ratio, % 80.6 ± 16.1 75.0 ± 11.5 74.1 ± 8.0 80.0 ± 8.2 71.5 ± 15.3 0.044 0.017
Blood eosinophils, % 2.0 ± 0.9 3.8 ± 6.0 5.6 ± 4.3 4.6 ± 9.5 2.5 ± 1.9 0.485 0.307
Sputum eosinophils, % 0.4 ± 0.8 1.9 ± 2.2 1.5 ± 1.3 2.1 ± 1.5 2.3 ± 3.2 <0.001 0.417
FeNO, ppb 16.1 ± 10.6 27.3 ± 27.6 34.3 ± 33.1 23.6 ± 24.5 23.4 ± 23.3 0.002 0.229
Anxiety and depression
 SAS score 31.8 ± 7.2 42.1 ± 10.8 42.0 ± 10.8 43.3 ± 9.8 41.2 ± 11.9 <0.001 0.763
 SDS score 34.0 ± 11.4 43.8 ± 11.0 44.9 ± 11.3 44.9 ± 8.7 41.6 ± 12.4 <0.001 0.416
  1. Plus–minus values are mean ± SD. Continuous data were compared with the use of the t test and One Way ANOVA, and categorical data were compared with the use of Pearson’s Chi square test. CA classic asthma, CVA cough-variant asthma, CTVA chest tightness variant asthma. The body-mass index (BMI) is the weight in kilograms divided by the square of the height in meters. FEV 1 forced expiratory volume in 1 s, FVC forced vital capacity, FeNO fractional exhaled nitric-oxide, SAS self-rating anxiety scale, SDS self-rating depression scale