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Table 3 IC50 values of BJAB, OCI-LY3 and SU-DHL-6 cells after 48 h of treatment with increasing concentrations of the c-MYC-inhibitor, LY294002, Rapamycin, PD98059, SB203580 and 2-DG (MTT assay)

From: Regulation of glucose uptake in lymphoma cell lines by c-MYC- and PI3K-dependent signaling pathways and impact of glycolytic pathways on cell viability

 

BJAB

OCI-LY3

SU-DHL-6

c-MYC-inh (µM)

10.23

6.48

6.67

LY294002 (µM)

10.66

9.67

10.94

Rapamycin (nM)

1021

912

1208

PD98059 (µM)

>50

>50

>50

SB203580 (µM)

>50

>50

>50

2-DG (mM)

4.65

4.07

2.86