Whole cohort | I-type | PB-type | |||||||
---|---|---|---|---|---|---|---|---|---|
N events | HR (95% CI) | P | N events | HR (95% CI) | P | N events | HR (95% CI) | P | |
CD1a+ TIDC | |||||||||
Univariable | 0.180 | 1 | 0.826 | 0.031 | |||||
Low | 153 (100) | 1 | 56 (28) | 0.85 | 97 (72) | 1 | |||
High | 15 (12) | 1.02 (0.82–2.93) | 5 (2) | (0.20–3.59) | 10 (10) | 2.09 (1.07–4.09) | |||
Multivariable | 0.271 | 0.532 | 0.022 | ||||||
Low | 153 (100) | 1 | 56 (28) | 1 | 97 (72) | 1 | |||
High | 15 (12) | 1.42 (0.76–2.67) | 5 (2) | 0.60 (0.12–2.98) | 10 (10) | 2.35 (1.13–4.87) | |||
CD68+ TAM | |||||||||
Univariable | 0.029 | 0.341 | 0.180 | ||||||
Low | 137 (86) | 1 | 55 (26) | 1 | 82 (60) | 1 | |||
High | 29 (24) | 1.67 (1.06–2.63) | 6 (4) | 1.68 (0.77–4.91) | 23 (20) | 1.42 (0.85–2.35) | |||
Multivariable | 0.102 | 0.501 | 0.125 | ||||||
Low | 137 (86) | 1 | 55 (26) | 1 | 82 (60) | 1 | |||
High | 29 (24) | 1.48 (0.93–2.36) | 6 (4) | 1.63 (0.39–6.74) | 23 (20) | 1.52 (0.89–2.67) | |||
CD163+ TAM | |||||||||
Univariable | 0.022 | 0.174 | 0.346 | ||||||
Low | 36 (17) | 1 | 20 (7) | 1 | 16 (10) | 1 | |||
High | 126 (89) | 1.84 (1.09–3.09) | 40 (22) | 1.81 (0.77–4.24) | 86 (67) | 1.38 (0.71–2.68) | |||
Multivariable | 0.164 | 0.067 | 0.608 | ||||||
Low | 36 (17) | 1 | 20 (7) | 1 | 16 (10) | 1 | |||
High | 126 (89) | 1.46 (0.85–2.57) | 40 (22) | 2.52 (0.94–6.81) | 86 (67) | 1.27 (0.58–2.58) | |||
MARCO+ | |||||||||
Univariable | 0.195 | 0.042 | 0.718 | ||||||
Low | 110 (68) | 1 | 38 (14) | 1 | 72 (54) | 1 | |||
High | 57 (43) | 1.29 (0.88–1.89) | 22 (15) | 2.14 (1.03–4.44) | 35 (28) | 1.09 (0.69-1.72) | |||
Multivariable | 0.002 | 1 | 0.220 | 1 | 0.124 | ||||
Low | 110 (68) | 1 | 38 (14) | 72 (54) | |||||
High | 57 (68) | 1.95 (1.28–2.98) | 22 (15) | 1.97 (0.67–5.80) | 35 (28) | 1.52 (0.89–2.59) |