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Fig. 5 | Journal of Translational Medicine

Fig. 5

From: Identification of new MUC1 epitopes using HLA-transgenic animals: implication for immunomonitoring

Fig. 5

In vivo cytotoxicity. Fluorescence-labelled splenocytes of HLA-matched mouse line were loaded with the indicated peptide and injected in either immunized or naive mice. Animals received concomitantly untreated splenocytes (no peptide) labelled with a different concentration of the fluorescent label. Killing was determined as described in “Methods”. a Each triangle represents the percentage of specific killing per mouse. Horizontal bar mean of all mice. b Table summarizing mean percentage of cytotoxicity and standard deviation. n number of animals analyzed. Peptides B7-ADPNRPAL, B35-FPARDTYHPM and A2-VLVCVLVAL showed a mean specific killing above 5% (shown in bold)

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