Fig. 4
From: Identification of new MUC1 epitopes using HLA-transgenic animals: implication for immunomonitoring
Fully human vs chimeric tetramer staining. Fully human HLA molecules or human-mouse chimera (human α1 + α2 + mouse Db α3) were loaded with the indicated peptide and used to stain splenocytes from immunized animals. a Mean percentage of stained CD8+ cells (n = 5 mice for fully human tetramer, n = 4 for chimeric constructs). b Fold increase in percentage of chimeric tetramer stained CD8+ cells/percentage of fully human tetramer stained CD8+ cells