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Table 1 Cardiac [15O]water and [68Ga]NODAGA-RGD PET

From: Imaging of αvβ3 integrin expression in experimental myocardial ischemia with [68Ga]NODAGA-RGD positron emission tomography

Animal

[15O]water PET

[68Ga]NODAGA-RGD PET

Ischemic area (% of the LV)

Remote SUVMean

Ischemic area SUVMean

Injured area SUVMax

1

19

0.68

0.71

0.95

2

17

0.37

0.56

0.67

3

35

0.52

0.70

1.11

4

32

0.47

0.56

0.74

5

19

0.36

0.54

0.72

6

36

0.65

0.79

0.94

7

37

0.42

0.41

0.59

8

43

0.45

0.57

0.70

Mean

30

0.49

0.61*

0.80 †

SD

10

0.12

0.12

0.18

  1. The size of ischemic area based on [15O]water PET during adenosine stress and myocardial [68Ga]NODAGA-RGD uptake shown as standardized uptake value (SUV) in the remote myocardium, in the ischemic area and at the site of the highest uptake (Max) within the ischemic area
  2. SUV standardized uptake value, LV left ventricle
  3. * p = 0.0034 vs. remote
  4. †p < 0.001 vs. remote
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Journal of Translational Medicine

ISSN: 1479-5876

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