Fig. 2
From: Molecular imaging biomarkers for cell-based immunotherapies
1H NMR spectra from cultured T cells obtained at 9.4 T. a Spectrum from previously non-stimulated resting T-cells shows lactate and other intra cellular metabolites, and very little alanine. b Spectrum from stimulated T cells with CD3/CD28 obtained under identical conditions of the spectra in a, which shows substantially (over 12-fold increase) higher lactate and alanine (3-fold increase) compared to that from non-stimulated resting T-cells (unpublished results from author’s laboratory)