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Table 1 Baseline clinical data

From: Exercise in claudicants increase or decrease walking ability and the response relates to mitochondrial function

 

Whole group (n = 28)

Positive responders (n = 8)

Negative responders (n = 8)

Comparison between subgroups

Mean ± SE

Mean ± SE

Mean ± SE

p value

Sex (female)

13 (44)

4 (50)

4 (50)

1.00

Age

69.2 ± 1.7

67.3 ± 3.45

69.3 ± 3.35

0.95

BMI

26.2 ± 0.7

26.6 ± 1.3

26.7 ± 0.9

0.95

Anamnestic walking distance (m)

348 ± 54

333 ± 120

194 ± 33

0.15

Pain free walking distance (m)

240 ± 33

178 ± 34

310 ± 100

0.12

Six minutes walking distance (m)

460 ± 10

448 ± 24

456 ± 21

0.33

Maximal walking distance (m)

591 ± 42

511 ± 46

561 ± 82

0.39

Claudication onset time (s)

270 ± 28

217 ± 50

294 ± 49

0.15

Peak walking time (s)

648 ± 61

667 ± 161

620 ± 81

0.40

VO2 peak (ml/kg/min)

18 ± 0.7

18 ± 2

18 ± 1

0.99

Maximal blood flow (ml/100 ml/min)

10.9 ± 0.9

10 ± 0.5

9.96 ± 2.4

0.96

Ankle brachial index

0.57 ± .0.03

0.54 ± 0.05

0.52 ± 0.04

0.76

Smoking

7 (25)

1 (13)

4 (50)

0.05

Aspirin

20 (71)

6 (75)

4 (50)

0.15

Statin

17 (60)

5 (62)

3 (38)

0.16

Previous vascular surgery

8 (29)

0 (0)

5 (62)

0.03

Systolic pressure

144 ± 4

134 ± 7

156 ± 10

0.04

Diastolic pressure

82 ± 2

77 ± 4

89 ± 3

0.01

  1. p values are calculated by t test for continuous variables and Chi square test for categorical variables between sub-group of negative and positive responders. Data are mean ± standard error of the mean (SE) for continuous variables, and numbers (proportions; %) for categorical variables