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Fig. 4 | Journal of Translational Medicine

Fig. 4

From: Osteoclast profile of medication-related osteonecrosis of the jaw secondary to bisphosphonate therapy: a comparison with osteoradionecrosis and osteomyelitis

Fig. 4

Analysis of (anti-)DC-STAMP staining: MRONJ (BP) vs. OM vs. ORN vs. control. a Shows a DC-STAMP+ osteoclast (arrowhead) and DC-STAMP+ mononuclear cells (arrows) within a MRONJ (BP) histological section. b Illustrates the number of DC-STAMP+ cells per ROI. c Depicts the number of DC-STAMP+ osteoclasts per ROI. d Illustrates the respective osteoclast labeling indices. * and ° mark statistical outliers. For detailed data, see Table 2. MRONJ (BP) medication-related osteonecrosis of the jaw secondary to bisphosphonate therapy, OC osteoclasts, OM osteomyelitis, ORN osteoradionecrosis, DC-STAMP dendritic cell-specific transmembrane protein, TRAP tartrate-resistant acid phosphatase

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