Table 3 Frequency of episodes that reported matching and/or ambiguous/other d-lactic acidosis (d-la) symptoms as a function of age and sex
ME/CFS ICC | d-La symptom overlap with ME/CFS | Episode frequencies | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Paediatric (≤17 years) | Adult (≥18 years) | Total | ||||||||||||||
Male (15 episodes) | Female (6 episodes) | NI (1 episode) | Total (22 episodes) | Male (20 episodes) | Female (17 episodes) | Total (37 episodes) | (59 episodes) | |||||||||
n | % | n | % | n | n | % | n | % | n | % | n | % | n | % | ||
A. Postexertional neuroimmune exhaustion | Matching | 8 | 53.3 | 1 | 16.7 | – | 9 | 40.9 | 2 | 20.0 | 4 | 23.5 | 6 | 16.2 | 15 | 25.4 |
Ambiguous/other | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | |
B. Neurological impairments | Matching | 12 | 80.0 | 6 | 100 | 1 | 19 | 86.4 | 18 | 90.0 | 15 | 88.3 | 33 | 89.2 | 52 | 88.1 |
Ambiguous/other | 11 | 73.3 | 2 | 33.3 | 1 | 14 | 63.6 | 17 | 85.0 | 14 | 82.4 | 31 | 83.8 | 45 | 76.3 | |
Ambiguous/other B1–B4 | 3 | 20.0 | 1 | 16.7 | 1 | 5 | 22.7 | 11 | 55.0 | 6 | 35.3 | 17 | 45.9 | 22 | 37.3 | |
Speech/language | 7 | 46.7 | 2 | 33.3 | 1 | 10 | 45.5 | 11 | 55.0 | 9 | 52.9 | 20 | 54.1 | 30 | 50.8 | |
Consciousness | 5 | 33.3 | – | – | – | 5 | 22.7 | 5 | 25.0 | 3 | 17.6 | 8 | 21.6 | 13 | 22.0 | |
C. Immune, gastrointestinal, genitourinary impairments | Matching | 3 | 20.0 | – | – | – | 3 | 13.6 | 6 | 30.0 | 4 | 23.5 | 9 | 24.3 | 12 | 20.3 |
Ambiguous/other | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | |
D. Energy production/transportation impairments | Matching | 8 | 53.3 | 3 | 50.0 | – | 11 | 50.0 | 7 | 35.0 | 2 | 11.8 | 9 | 24.3 | 20 | 33.9 |
Ambiguous/other | – | – | – | – | – | – | – | 2 | 10.0 | – | – | 2 | 5.4 | 2 | 3.4 | |
Mood/behavior | Matching | 2 | 13.3 | 1 | 16.7 | – | 3 | 13.6 | 2 | 10.0 | 3 | 17.6 | 5 | 13.5 | 8 | 13.6 |
Ambiguous/other | 6 | 40.0 | – | – | – | 6 | 27.3 | 4 | 20.0 | 3 | 17.6 | 7 | 18.9 | 13 | 22.0 | |
Uncategorized d-la symptoms | ||||||||||||||||
| Â | Metabolic acidosis | 15 | 100 | 6 | 100 | 1 | 22 | 100 | 20 | 100 | 16 | 94.1 | 36 | 97.3 | 58 | 98.3 |
|  | Other abnormalities | 4 | 26.7 | – | – | – | 4 | 18.2 | 6 | 30.0 | 2 | 11.8 | 7 | 18.9 | 11 | 18.6 |