Distinct expression profile of HCMV encoded miRNAs in plasma from oral lichen planus patients

Table 1 Demographic and clinical features of OLP patients and healthy controls in the present study

Variable	Training set			Validation set			HCMV titers set			Exosome set
Variable	Cases	Controls	P value	Cases	Controls	P value	Cases	Controls	P value	Cases
Number	21	18		41	33		13	12		20
Age, years^a	46.48 (9.08)	44.78 (4.18)	0.47^b	46.59 (13.19)	46.45 (4.97)	0.96^b	49.3 (6.2)	46.9 (5.5)	0.68^b	45.6 (6.3)
Sex, n			0.75^c			0.84^c			0.87^c
Male	6 (29%)	6 (33%)		13 (32%)	12 (39%)		5 (38%)	5 (41%)		7 (35%)
Female	15 (71%)	12 (67%)		28 (68%)	21 (61%)		8 (62%)	7 (59%)		13 (65%)
Type of OLP, n
Reticular OLP	10 (48%)			21 (51%)			7 (54%)			10 (50%)
Erosive OLP	11 (52%)			20 (49%)			6 (46%)			10 (50%)
Anti-HCMV IgG, n			0.27^c			0.11^c			0.29^c
Positive	21 (100%)	17 (94%)		41 (100%)	31 (94%)		13 (100%)	11 (92%)		20 (100%)
Negative	0 (0%)	1 (6%)		0 (0%)	2 (6%)		0 (0%)	1 (8%)		0 (0%)
Anti-HCMV IgM, n
Positive	0 (0%)	0 (0%)		0 (0%)	0 (0%)		0 (0%)	0 (0%)		0 (0%)
Negative	21 (100%)	18 (100%)		41 (100%)	33 (100%)		13 (100%)	12 (100%)		20 (100%)
HCV, n			0.18^c			0.04^c			0.16^c
Positive	2 (9.5%)	0 (0%)		5 (12.2%)	0 (0%)		2 (15.4%)	0 (0%)		3 (15%)
Negative	19 (90.5%)	18 (100%)		36 (87.8%)	33 (100%)		11 (74.6%)	12 (100%)		17 (85%)
EBV, n						0.2^c
Positive	0 (0%)	0 (0%)		2 (4.9%)	0 (0%)		0 (0%)	0 (0%)		1 (5%)
Negative	21 (100%)	18 (100%)		39 (95.1%)	33 (100%)		13 (100%)	12 (100%)		19 (95%)
HIV, n
Positive	0 (0%)	0 (0%)		0 (0%)	0 (0%)		0 (0%)	0 (0%)		0 (0%)
Negative	21 (100%)	18 (100%)		41 (100%)	33 (100%)		13 (100%)	12 (100%)		20 (100%)

ISSN: 1479-5876