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Table 1 Demographic and clinical features of OLP patients and healthy controls in the present study

From: Distinct expression profile of HCMV encoded miRNAs in plasma from oral lichen planus patients

Variable Training set Validation set HCMV titers set Exosome set
Cases Controls P value Cases Controls P value Cases Controls P value Cases
Number 21 18   41 33   13 12   20
Age, yearsa 46.48 (9.08) 44.78 (4.18) 0.47b 46.59 (13.19) 46.45 (4.97) 0.96b 49.3 (6.2) 46.9 (5.5) 0.68b 45.6 (6.3)
Sex, n    0.75c    0.84c    0.87c  
 Male 6 (29%) 6 (33%)   13 (32%) 12 (39%)   5 (38%) 5 (41%)   7 (35%)
 Female 15 (71%) 12 (67%)   28 (68%) 21 (61%)   8 (62%) 7 (59%)   13 (65%)
Type of OLP, n
 Reticular OLP 10 (48%)    21 (51%)    7 (54%)    10 (50%)
 Erosive OLP 11 (52%)    20 (49%)    6 (46%)    10 (50%)
Anti-HCMV IgG, n    0.27c    0.11c    0.29c  
 Positive 21 (100%) 17 (94%)   41 (100%) 31 (94%)   13 (100%) 11 (92%)   20 (100%)
 Negative 0 (0%) 1 (6%)   0 (0%) 2 (6%)   0 (0%) 1 (8%)   0 (0%)
Anti-HCMV IgM, n
 Positive 0 (0%) 0 (0%)   0 (0%) 0 (0%)   0 (0%) 0 (0%)   0 (0%)
 Negative 21 (100%) 18 (100%)   41 (100%) 33 (100%)   13 (100%) 12 (100%)   20 (100%)
HCV, n    0.18c    0.04c    0.16c  
 Positive 2 (9.5%) 0 (0%)   5 (12.2%) 0 (0%)   2 (15.4%) 0 (0%)   3 (15%)
 Negative 19 (90.5%) 18 (100%)   36 (87.8%) 33 (100%)   11 (74.6%) 12 (100%)   17 (85%)
EBV, n       0.2c     
 Positive 0 (0%) 0 (0%)   2 (4.9%) 0 (0%)   0 (0%) 0 (0%)   1 (5%)
 Negative 21 (100%) 18 (100%)   39 (95.1%) 33 (100%)   13 (100%) 12 (100%)   19 (95%)
HIV, n
 Positive 0 (0%) 0 (0%)   0 (0%) 0 (0%)   0 (0%) 0 (0%)   0 (0%)
 Negative 21 (100%) 18 (100%)   41 (100%) 33 (100%)   13 (100%) 12 (100%)   20 (100%)
  1. aAge data are presented as the mean ± SD
  2. bStudent t test
  3. cTwo-sided χ2 test