Skip to main content
Fig. 1 | Journal of Translational Medicine

Fig. 1

From: Sphingosine kinase 1 expression enhances colon tumor growth

Fig. 1

SphK1 KO mice significantly reduce colon carcinogenesis. SphK1 KO mice significantly reduced colon tumor incidence (number of mice with tumors, a) including total tumor (adenoma plus adenocarcinoma), adenoma, and adenocarcinoma; tumor multiplicity (number of tumors per mouse, b); tumor volume (c) as compared to WT mice. Tumor volume is positively correlated to S1P levels in blood in WT mice (d). The data is presented as mean ± SEM; *P < 0.05 and ***P < 0.001 vs. wild type

Back to article page