Standardization of platelet releasate products for clinical applications in cell therapy: a mathematical approach

Table 1 Composition of manufactured supernatant rich in growth factors pool batches. Identification matrix of single donor supernatant rich in growth factors (n = 44) utilized used to create the n = 10 supernatant rich in growth factors pool batches (from A to J, see “Methods”). To produce SRGF pools batches A and B, 2 ml of single donor SRGF specimens were mixed together. Otherwise, to create SRGF pool batches C–J, only 500 μl of each single donor SRGF specimens were utilized

Batch A	Batch B	Batch C	Batch D	Batch E	Batch F	Batch G	Batch H	Batch I	Batch J
1	3	1	2	1	1	2	2	2	4
8	9	6	4	2	5	3	3	3	5
11	14	8	6	4	7	7	8	4	6
13	15	10	7	7	11	10	9	5	8
14	16	13	11	8	12	11	13	9	9
15	18	20	16	10	15	12	14	12	16
16	20	21	21	27	18	19	16	15	17
17	24	22	22	28	22	20	17	19	19
21	25	25	23	30	26	21	19	23	23
25	26	27	24	31	27	23	20	34	27
29	27	30	26	36	29	24	22	35	29
33	28	31	31	38	32	29	28	36	32
34	33	32	33	39	35	30	30	37	33
38	36	34	36	40	39	31	32	40	37
43	40	35	42	43	42	41	37	41	39
44	41	39	43	44	43	43	44	44	42

ISSN: 1479-5876

Batch A	Batch B	Batch C	Batch D	Batch E	Batch F	Batch G	Batch H	Batch I	Batch J
1	3	1	2	1	1	2	2	2	4
8	9	6	4	2	5	3	3	3	5
11	14	8	6	4	7	7	8	4	6
13	15	10	7	7	11	10	9	5	8
14	16	13	11	8	12	11	13	9	9
15	18	20	16	10	15	12	14	12	16
16	20	21	21	27	18	19	16	15	17
17	24	22	22	28	22	20	17	19	19
21	25	25	23	30	26	21	19	23	23
25	26	27	24	31	27	23	20	34	27
29	27	30	26	36	29	24	22	35	29
33	28	31	31	38	32	29	28	36	32
34	33	32	33	39	35	30	30	37	33
38	36	34	36	40	39	31	32	40	37
43	40	35	42	43	42	41	37	41	39
44	41	39	43	44	43	43	44	44	42

Batch A	Batch B	Batch C	Batch D	Batch E	Batch F	Batch G	Batch H	Batch I	Batch J
1	3	1	2	1	1	2	2	2	4
8	9	6	4	2	5	3	3	3	5
11	14	8	6	4	7	7	8	4	6
13	15	10	7	7	11	10	9	5	8
14	16	13	11	8	12	11	13	9	9
15	18	20	16	10	15	12	14	12	16
16	20	21	21	27	18	19	16	15	17
17	24	22	22	28	22	20	17	19	19
21	25	25	23	30	26	21	19	23	23
25	26	27	24	31	27	23	20	34	27
29	27	30	26	36	29	24	22	35	29
33	28	31	31	38	32	29	28	36	32
34	33	32	33	39	35	30	30	37	33
38	36	34	36	40	39	31	32	40	37
43	40	35	42	43	42	41	37	41	39
44	41	39	43	44	43	43	44	44	42

Batch A	Batch B	Batch C	Batch D	Batch E	Batch F	Batch G	Batch H	Batch I	Batch J
1	3	1	2	1	1	2	2	2	4
8	9	6	4	2	5	3	3	3	5
11	14	8	6	4	7	7	8	4	6
13	15	10	7	7	11	10	9	5	8
14	16	13	11	8	12	11	13	9	9
15	18	20	16	10	15	12	14	12	16
16	20	21	21	27	18	19	16	15	17
17	24	22	22	28	22	20	17	19	19
21	25	25	23	30	26	21	19	23	23
25	26	27	24	31	27	23	20	34	27
29	27	30	26	36	29	24	22	35	29
33	28	31	31	38	32	29	28	36	32
34	33	32	33	39	35	30	30	37	33
38	36	34	36	40	39	31	32	40	37
43	40	35	42	43	42	41	37	41	39
44	41	39	43	44	43	43	44	44	42