Table 1 Baseline characteristics of the study cohort
From: Correlation of cell-free DNA plasma concentration with severity of non-alcoholic fatty liver disease
|  | Controls n = 13 | NAFLD cohort n = 58 |
|---|---|---|
Anthropometry | ||
 Sex (male/female) | 6 (46.2%)/7 (53.8%) | 32 (55.2%)/26 (44.8%) |
 Age (yearsa) | 37.7 ± 11.5 | 62.1 ± 11.0 |
 BMI (kg/m2a) | 22.4 ± 2.1 | 28.2 ± 3.5 |
  <25 (n) | 11 (84.6%) | 12 (20.7%) |
  25–30 (n) | 2 (15.4%) | 30 (51.7%) |
  30–35 (n) | 0 (0%) | 15 (25.9%) |
  >35 (n) | 0 (0%) | 1 (1.7%) |
 Waist-to-hip (ratioa) | 0.87 ± 0.14 | 0.96 ± 0.09 |
 Diabetes (n) | 0 (0%) | 37 (63.8%) |
Laboratory values | ||
 HbA1c (%b) | 5.0 (4.7–5.4) | 5.7 (4.6–8.0) |
 ALT/ULN (ratiob) | 0.4 (0.3–0.6) | 0.9 (0.3–3.3) |
 AST/ULN (ratiob) | 0.5 (0.4–0.7) | 0.8 (0.3–2.1) |
 Ferritin/ULN (ratiob) | 0.3 (0.05–2.0) | 0.7 (0.1–5.5) |
Non-invasive liver assessment | ||
 1H-MRS (rHLCb) | 0.8 (0–8.6) | 12.8 (1.2–41.1) |
 CAP (dB/mb) | 210 (100–231) | 310 (249–397) |
 Liver stiffness (kPab) | 4.4 (2.3–5.9) | 5.3 (1.9–70.6) |