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Table 1 Baseline characteristics of the study cohort

From: Correlation of cell-free DNA plasma concentration with severity of non-alcoholic fatty liver disease

  Controls n = 13 NAFLD cohort n = 58
Anthropometry
 Sex (male/female) 6 (46.2%)/7 (53.8%) 32 (55.2%)/26 (44.8%)
 Age (yearsa) 37.7 ± 11.5 62.1 ± 11.0
 BMI (kg/m2a) 22.4 ± 2.1 28.2 ± 3.5
  <25 (n) 11 (84.6%) 12 (20.7%)
  25–30 (n) 2 (15.4%) 30 (51.7%)
  30–35 (n) 0 (0%) 15 (25.9%)
  >35 (n) 0 (0%) 1 (1.7%)
 Waist-to-hip (ratioa) 0.87 ± 0.14 0.96 ± 0.09
 Diabetes (n) 0 (0%) 37 (63.8%)
Laboratory values
 HbA1c (%b) 5.0 (4.7–5.4) 5.7 (4.6–8.0)
 ALT/ULN (ratiob) 0.4 (0.3–0.6) 0.9 (0.3–3.3)
 AST/ULN (ratiob) 0.5 (0.4–0.7) 0.8 (0.3–2.1)
 Ferritin/ULN (ratiob) 0.3 (0.05–2.0) 0.7 (0.1–5.5)
Non-invasive liver assessment
 1H-MRS (rHLCb) 0.8 (0–8.6) 12.8 (1.2–41.1)
 CAP (dB/mb) 210 (100–231) 310 (249–397)
 Liver stiffness (kPab) 4.4 (2.3–5.9) 5.3 (1.9–70.6)
  1. BMI body mass index, HbA1c hemoglobin A1c, ALT alanine aminotransferase, AST aspartate aminotransferase, ULN upper limit of normal, 1 H-MRS single-proton magnetic resonance spectroscopy, CAP controlled attenuation parameter, rHLC relative hepatic lipid content
  2. a Values presented as mean and standard deviation
  3. b Values presented as median and range