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Table 4 The number of genes targeted by the miRNAs in the altered pathways

From: Bovis Bacillus Calmette–Guerin (BCG) infection induces exosomal miRNA release by human macrophages

Pathways Gene p value
Pathways in fatty acid metabolism
 Fatty acid biosynthesis 2 0.000000000684
 Fatty acid metabolism 12 0.00000154
 Fatty acid elongation 7 0.000738
 Steroid biosynthesis 6 0.00631
 2-Oxocarboxylic acid metabolism 6 0.0165
Pathways in amino acids metabolism
 Phenylalanine, tyrosine and tryptophan biosynthesis 4 0.000713
 Valine, leucine and isoleucine degradation 12 0.0310
 Lysine degradation 16 0.0421
Pathways of energy production and sugar metabolism
 Central carbon metabolism in cancer 19 0.00435
 2-Oxocarboxylic acid metabolism 6 0.0165
 Glycosaminoglycan biosynthesis—heparan sulfate/heparin 9 0.0113
 Proteoglycans 49 0.0337
Pathways in infection
 Bacterial invasion of epithelial cells 23 0.0310
 Endocytosis 51 0.0337
 ECM-receptor interaction 16 0.00153
 Adheres junction 21 0.00730
 Inositol phosphate metabolism 15 0.0201
Cell signaling pathways
 Phosphatidylinositol signaling system 21 0.0489
 TGF-beta signaling pathway 18 0.0489
Pathways in bacterial digestion
 Proteasome 3 0.0138
 Ubiquitin mediated proteolysis 7 0.00566