Skip to main content

Table 3 Functional pathways identified in mRNA targets for miRNAs

From: Bovis Bacillus Calmette–Guerin (BCG) infection induces exosomal miRNA release by human macrophages

  p value Number of miRNAs in each pathway
Pathways in bacterial digestion
 Proteasome 0.0139 3
 Ubiquitin-mediated proteolysis 0.0057 7
Pathways in infection process
 Bacterial invasion of epithelial cells 0.0310 7
 Endocytosis 0.0337 8
 ECM-receptor interaction 0.00153 4
 Adherents junction 0.00730 4
 Inositol phosphate metabolism 0.00201 4
Pathways in fatty acid metabolism
 Fatty acid biosynthesis 0.00000000684 3
 Fatty acid metabolism 0.00000154 5
 Fatty acid elongation 0.000738 3
 Steroid biosynthesis 0.00631 3
 2-Oxocarboxylic acid metabolism 0.0165 3
Pathways in amino acids metabolism
 Phenylalanine, tyrosine and tryptophan biosynthesis 0.000713 3
 Valine, leucine and isoleucine degradation 0.0310 6
 Lysine degradation 0.0421 6
Pathways for energy production and sugar metabolism
 Central carbon metabolism 0.00435 5
 2-Oxocarboxylic acid metabolism 0.0165 3
 Glycosaminoglycan biosynthesis—heparan sulfate/heparin 0.0113 3
 Proteoglycans 0.0337 8
Cell signaling pathways
 Phosphatidylinositol signaling system 0.0489 5
 TGF-beta signaling pathway 0.0489 4