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Table 5 Relevant patients’ characteristics at the time of accrual in clinical trials on dendritic cell vaccination in glioblastoma multiforme

From: A phase II trial of autologous dendritic cell vaccination and radiochemotherapy following fluorescence-guided surgery in newly diagnosed glioblastoma patients

 

Mean age

KPS (100/90/80/≤70)

RPA (class 3/4/5)

OS (months)

aPrins8

49.7

(7%; 77%; 20%; 7%)

(60%; 33%; 7%)d

35.9

aArdon9

50.4

N/A

(12%/87%/0%)

24.0

bSampson25

52.4

(39%; 39%; 22%; 0%)

(28%/72%/0%)d

26.0

cPhuphanich26

55.3

(12%; 62%; 12%; 12%)

(19%/69%/12%)d

38.4

Present data (intention-to-treat)

58.8

(6%; 23%; 36%; 36%)

(10%/42%/48%)

23.4

  1. KPS Karnofsky performance status, RPA recursive partition analysis, OS overall survival, N/A not available
  2. aIt excludes patients with steroids after radiotherapy
  3. bIt excludes patients progressing after radiotherapy
  4. cIt excludes patients with more than 4 mg/day of dexamethasone
  5. dRPA classes estimated based on provided data; in doubt, the highest level was assigned