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Table 3 Concentrations of serum cytokines

From: A phase II trial of autologous dendritic cell vaccination and radiochemotherapy following fluorescence-guided surgery in newly diagnosed glioblastoma patients

 

Before vaccination

After vaccination

IL-1β

52.5 ± 33.5

53.7 ± 49.1

IL-10

321.6 ± 260.3

272.1 ± 249.3

IFN-α

70.9 ± 56.9

79.3 ± 64.8

IL-6

209.5 ± 280.6

160.4 ± 134

IL-12

134.2 ± 86.4

242.8 ± 581.7

RANTES

10,159.9 ± 820

9828 ± 1289.8

EOTAXIN

1490.8 ± 461.1

1412.4 ± 465.6

IL-13

229.8 ± 125.3

228.3 ± 112.4

IL-15

382.6 ± 68.6

402.8 ± 130.7

IL-17

194.2 ± 131

219 ± 152

MIP-1α

46.33 ± 17.8

76 ± 160

GM-CSF

139.1 ± 96.9

179.4 ± 264

MIP-1β

109.6 ± 48.1

100.4 ± 57.4

MCP-1

868.1 ± 637.6

717.1 ± 368.8

IL-5

112.7 ± 151.2

81.2 ± 77.8

IFN-γ

116.7 ± 82

108.3 ± 75.9

TNF-α

28.52 ± 42.3

31.1 ± 37.9

IL-1RA

218.7 ± 143.9

133.5 ± 71

IL-2

33.8 ± 25

27.4 ± 20.4

IL-7

366.5 ± 194.4

365.9 ± 194.9

IP-10

1846.1 ± 3590.6

690.4 ± 1170.4

IL-2R

296.9 ± 114.5

251 ± 55.6

MIG

272.7 ± 554.2

78.4 ± 61.8

IL-4

57.9 ± 58.2

44.7 ± 54.4

IL-8

182.7 ± 196.5

140.5 ± 67.5

  1. Changes in cytokines profiles after vaccination were evaluated in 20 patients in serum samples obtained before and after vaccination by Multiplex Bead Immunoassay Kit (Invitrogen, Carlsbad, CA, USA) for simultaneous quantitative determination of 25 Human Cytokines. The median and standard deviation of all patients before and post vaccination for each cytokine are included in this table