Table 2 Overview of hemophilia B canine studies
From: Evaluation of engineered AAV capsids for hepatic factor IX gene transfer in murine and canine models
Dog | Serotype | Route | Dose (vg/kg) | Weight (kg) | Age (year month) | Gender |
|---|---|---|---|---|---|---|
O19 | AAV2(Y-F)-M3 | PV | 2 × 1011 | 27.8 | 2 year 1 month | Male |
O58 | AAV2(Y-F)-M3 | PV | 6 × 1011 | 23.2 | 2 year 6 month | Male |
Bruce | AAV2-LiC | IV | 6 × 1011 | 21.4 | 4 year 1 month | Male |