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Fig. 2 | Journal of Translational Medicine

Fig. 2

From: Distinct gene expression profiles associated with Notch ligands Delta-like 4 and Jagged1 in plaque material from peripheral artery disease patients: a pilot study

Fig. 2

Expression of Notch pathway components and inflammatory markers in plaque material. Relative expression levels of Notch target genes (a) and ligands (b) and of genes related to vascular smooth muscle cells transdifferentiation (c) in plaque material. Relative changes in mRNA expression levels were calculated according to the ΔΔCt method relative to the patient with the lowest expression level of the target gene (grey bar) as described in Materials and Methods-Online. ****P < 0.0001, ***P < 0.001, **P < 0.01 and *P < 0.05, significantly different from the control (grey bar)

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