Fig. 4

Flow cytometry analysis of expression of NK1R in peripheral blood leukocytes of patients with AD and healthy control (HC) subjects. a Representative graphs of the percentage of NK1R⁺ cells out of the corresponding leukocyte population. (A), (B), (C), (D), (E) and (F) represent NK1R⁺ populations of CD4⁺ (helper T cells), CD8⁺ (cytotoxic T cells), CD14⁺ (monocytes), CD16⁺ (neutrophils), CD19⁺ (B cells), and CD123⁺HLA-DR⁻ cells (basophils) in HC subjects, respectively. (G), (H), (I), (J), (K) and (L) represent NK1R⁺ populations of CD4⁺, CD8⁺, CD14⁺, CD16⁺, CD19⁺, and CD123⁺HLA-DR⁻ cells in patients with AD, respectively. b The median values of the percentage of NK1R⁺ cells from AD and HC subjects. Each symbol represents the value from one subject. The median value is indicated by a horizontal line. P < 0.05 was considered statistically significant