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Table 2 Overall agreement in patient subgroups: all cases versus not equivocal only

From: Her2 assessment using quantitative reverse transcriptase polymerase chain reaction reliably identifies Her2 overexpression without amplification in breast cancer cases

Comparisons Overall agreement (95% CI)
All cases (153) Non equivocal only (124)
FISH vs DNA copy number 94.10 (89.10–97.30) 97.58 (93.13–99.17)
FISH vs mRNA expression 90.80 (85.70–94.90) 95.40 (94.31–99.56)
DNA copy number vs mRNA expression 90.20 (84.46–93.97) 94.70 (90.91–98.27)
  1. CI confidence interval, FISH fluorescence in situ hybridization, DNA deoxyribonucleic acid, mRNA messenger ribonucleic acid