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Table 3 Incidence of tumor formation after intratibial injection of MCF-7 over-expressed Snail and knocked down ESR1

From: Role of estrogen receptors and Src signaling in mechanisms of bone metastasis by estrogen receptor positive breast cancers

  Tumor (+) Tumor (−) p value
MCF-7 o/e Snail 23 8 0.014*
MCF-7 o/e Snail ∆ESR1 1 5
  1. MCF-7 o/e Snail, MCF-7 over-expressed Snail protein. MCF-7 o/e Snail, ∆ESR1, MCF-7 over-expressed Snail protein and ESR1 gene knocked down simultaneously. Intratibial injection of cancer cells were described in “Methods
  2. * p value analyzed by Fisher exact test