Table 4 Correlation between TREM-1 with M1 and M2 macrophage markers in omentum and liver tissues
Target genes correlation | TREM1 expression in obese non-diabetics (OND) | TREM1 expression in obese diabetics (OD) | Correlation (R); p value |
|---|---|---|---|
Increased TREM-1 (OND-14/16; OD-17/17) association with other genes in omentumsamples | |||
 CD68 | 14/14 (100%) | 17/17 (100%) | NS |
 CD86 | 14/14 (100%) | 17/17 (100%) | NS |
 CCR-7 | 11/14 (78.6%) | 17/17 (100%) | NS |
 iNOS | 11/14 (78.6%) | 17/17 (100%) | NS |
 IFNγ | 10/14 (71.4%) | 17/17 (100%)* | R = 0.424; p = 0.032 |
 TNF-α | 14/14 (100%) | 17/17 (100%) | NS |
 IL-6 | 12/14 (85.7%) | 16 (94.1%) | NS |
 TREM-2 | 13/14 (92.9%) | 17/17 (100%) | NS |
 CD206 | 11/14 (78.6%) | 17/17 (100%) | NS |
 CD163 | 12/14 (85.7%) | 17/17 (100%) | NS |
 IL-4 | 9/14 (64.3%) | 17/17 (100%)* | R = 0.483; p = 0.012 |
 IL-10 | 9/14 (64.3%) | 17/17 (100%)* | R = 0.483; p = 0.012 |
 MCP-1 | 13/14 (92.9%) | 17/17 (100%) | NS |
 CCR-2 | 13/14 (92.9%) | 17/17 (100%) | NS |
 CCR-5 | 13/14 (92.9%) | 17/17 (100%) | NS |
Increased TREM-1 (OND-9/16; OD-17/17) association with other genes in liver samples | |||
 CD68 | 6/9 (66.7%) | 17/17 (100%)* | R = 0.496; p = 0.032 |
 CD86 | 6/9 (66.7%) | 17/17 (100%)* | R = 0.496; p = 0.032 |
 CCR-7 | 5/9 (55.6%) | 17/17 (100%)** | R = 0.586; p = 0.008 |
 iNOS | 5/9 (55.6%) | 17/17 (100%)** | R = 0.586; p = 0.008 |
 IFNγ | 6/9 (66.7%) | 17/17 (100%)* | R = 0.496; p = 0.032 |
 TNF-α | 6/9 (66.7%) | 15/17 (88.2%) | NS |
 IL-6 | 6/9 (66.7%) | 12/17 (70.6%) | NS |
 TREM-2 | 9/9 (100%) | 13/17 (76.5%) | NS |
 CD206 | 4/9 (44.4%) | 16/17 (100%)* | R = 0.561; p = 0.010 |
 CD163 | 2/9 (22.2%) | 13/17 (76.5%)* | R = 0.522; p = 0.012 |
 IL-4 | 6/9 (66.7%) | 17/17 (100%)* | R = 0.496; p = 0.032 |
 IL-10 | 4/9 (44.4%) | 10/17 (58.8%) | NS |
 MCP-1 | 6/9 (66.7%) | 17/17 (100%)* | R = 0.496; p = 0.032 |
 CCR-2 | 6/9 (66.7%) | 17/17 (100%)* | R = 0.496; p = 0.032 |
 CCR-5 | 6/9 (66.7%) | 17/17 (100%)* | R = 0.496; p = 0.032 |