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Fig. 5 | Journal of Translational Medicine

Fig. 5

From: RETRACTED ARTICLE: TREM-1 associated macrophage polarization plays a significant role in inducing insulin resistance in obese population

Fig. 5

Mean fluorescence intensity (MFI) of M1 and M2 macrophage markers using immunofluorescence staining in the biopsy samples of study subjects. A MFI of target genes in omentum biopsy samples. B MFI of target genes in subcutaneous biopsy samples. C MFI of target genes in liver biopsy samples. MFI for pan macrophage marker (CD68), M1 macrophage markers (TREM-1, CD86, CCR-7, iNOS, IFN-γ, TNF-α, IL-6, MCP-1, CCR-2 and CCR-5) and M2 macrophage markers (TREM-2, CD163, CD206, IL-4 and IL-10) of each group biopsy samples was measured in the stained slides using Image-J software. The MFI levels of these targets in biopsy samples were compared between non-obese, obese non-diabetics and obese diabetics using One-way ANOVA for continuous variables. Data were shown as mean ± SD (N = 5 non-obese; 16 obese non-diabetics; 17 obese diabetics); *p < 0.05, **p < 0.01, ***p < 0.001, and ****p < 0.0001

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