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Fig. 1 | Journal of Translational Medicine

Fig. 1

From: Adenovirus-mediated CD40L gene transfer increases Teffector/Tregulatory cell ratio and upregulates death receptors in metastatic melanoma patients

Fig. 1

PBMCs were evaluated for the presence of T effector cells (CD3+CD4−CD127+), Tregulatory cells (CD3+CD4+FoxP3+CD127−) and NK cells (CD3−CD16+CD56+). a, b The percentage of T effector cells and NK cells before treatment (pre) and 3 weeks post treatment initiation (post) were displayed against survival. c, d The ratio of Teff/Treg and NK/Treg were calculated pre and post 3 weeks. eh Patient plasma was analyzed by ProSeek proteomics at baseline (pre) and after 3 weeks post treatment initiation (post) and proteins connected to T cell activity are displayed. Statistical calculations were done by GraphPad Prism utilizing Wilcoxon test for paired samples

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