Fig. 3
From: Specific circulating microRNA signature of bicuspid aortic valve disease
The expression of circulating miR-718 is affected by the dilation of the ascending aorta. A RT-qPCR validation of the effect of the ascending aortic dilation on the expression levels of miR-130a and miR-718 in the plasma. The specific effects of the valve morphology and aortic dilation were analysed for miR-130a (B) and miR-718 (C). Two asterisks Significant values (p < 0.001; unpaired t test). The bars with different letters are significantly different (one-way ANOVA, Tukey test, p < 0.05)