Fig. 2
From: Specific circulating microRNA signature of bicuspid aortic valve disease
The expression levels of miR-122, miR-130a and miR-486 are influenced by the morphology of the aortic valve. a The validation of the miRNA candidates for aortic morphology was performed by RT-qPCR. Two asterisks Significant values (p < 0.001; unpaired t test). b The pathways of intracellular signal transduction were significantly enriched by the predicted target genes of miR-122, miR-130a and miR-486. c Interactive miRNA-gene network regarding the TGF-beta signalling pathway. TAV tricuspid aortic valve, BAV bicuspid aortic valve, TGF transforming growth factor