Table 2 List of the 100 most dysregulated genes due to the 24h effect of BE

ENSG00000125257

ABCC4

ATP-binding cassette, sub-family C (CFTR/MRP), member 4

Up-regulated

ENSG00000114770

ABCC5

ATP-binding cassette, sub-family C (CFTR/MRP), member 5

Down-regulated

ENSG00000173208

ABCD2

ATP-binding cassette, sub-family D (ALD), member 2

Up-regulated

ENSG00000151726

ACSL1

Acyl-CoA synthetase long-chain family member 1

Down-regulated

ENSG00000135074

ADAM19

ADAM metallopeptidase domain 19 (meltrin beta)

Down-regulated

ENSG00000154027

AK5

Adenylate kinase 5

Up-regulated

ENSG00000151150

ANK3

Ankyrin 3, node of Ranvier (ankyrin G)

Up-regulated

ENSG00000206560

ANKRD28

Ankyrin repeat domain 28

Up-regulated

ENSG00000118520

ARG1

Arginase, liver

Down-regulated

ENSG00000196914

ARHGEF12

Rho guanine nucleotide exchange factor (GEF) 12

Up-regulated

ENSG00000156802

ATAD2

ATPase family, AAA domain containing 2

Up-regulated

ENSG00000085224

ATRX

Alpha thalassemia/mental retardation syndrome X-linked (RAD54 homolog, S. cerevisiae)

Up-regulated

ENSG00000023445

BIRC3

baculoviral IAP repeat-containing 3

Up-regulated

ENSG00000102010

BMX

BMX non-receptor tyrosine kinase

Down-regulated

ENSG00000136492

BRIP1

BRCA1 interacting protein C-terminal helicase 1

Up-regulated

ENSG00000197603

C5orf42

Chromosome 5 open reading frame 42

Up-regulated

ENSG00000152495

CAMK4

Calcium/calmodulin-dependent protein kinase IV

Up-regulated

ENSG00000137812

CASC5

Cancer susceptibility candidate 5

Up-regulated

ENSG00000138778

CENPE

Centromere protein E, 312 kDa

Up-regulated

ENSG00000198707

CEP290

Centrosomal protein 290 kDa

Up-regulated

ENSG00000106034

CPED1

Cadherin-like and PC-esterase domain containing 1

Up-regulated

ENSG00000103196

CRISPLD2

Cysteine-rich secretory protein LCCL domain containing 2

Down-regulated

ENSG00000146122

DAAM2

Dishevelled associated activator of morphogenesis 2

Down-regulated

ENSG00000035664

DAPK2

Death-associated protein kinase 2

Down-regulated

ENSG00000137628

DDX60

DEAD (Asp-Glu-Ala-Asp) box polypeptide 60

Up-regulated

ENSG00000174485

DENND4A

DENN/MADD domain containing 4A

Up-regulated

ENSG00000135905

DOCK10

Dedicator of cytokinesis 10

Up-regulated

ENSG00000147459

DOCK5

Dedicator of cytokinesis 5

Down-regulated

ENSG00000088387

DOCK9

Dedicator of cytokinesis 9

Up-regulated

ENSG00000178904

DPY19L3

Dpy-19-like 3 (C. elegans)

Down-regulated

ENSG00000134765

DSC1

Desmocollin 1

Up-regulated

ENSG00000135636

DYSF

Dysferlin, limb girdle muscular dystrophy 2B (autosomal recessive)

Down-regulated

ENSG00000198919

DZIP3

DAZ interacting protein 3, zinc finger

Up-regulated

ENSG00000102189

EEA1

Early endosome antigen 1

Up-regulated

ENSG00000151491

EPS8

Epidermal growth factor receptor pathway substrate 8

Up-regulated

ENSG00000089048

ESF1

ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae)

Up-regulated

ENSG00000198734

F5

Coagulation factor V (proaccelerin, labile factor)

Down-regulated

ENSG00000140525

FANCI

Fanconi anemia, complementation group I

Up-regulated

ENSG00000138829

FBN2

Fibrillin 2 (congenital contractural arachnodactyly)

Down-regulated

ENSG00000139132

FGD4

FYVE, RhoGEF and PH domain containing 4

Down-regulated

ENSG00000122025

FLT3

Fms-related tyrosine kinase 3

Down-regulated

ENSG00000161791

FMNL3

Formin-like 3

Up-regulated

ENSG00000073910

FRY

Furry homolog (Drosophila)

Down-regulated

ENSG00000162654

GBP4

Guanylate binding protein 4

Up-regulated

ENSG00000182885

GPR97

G protein-coupled receptor 97

Down-regulated

ENSG00000106070

GRB10

Growth factor receptor-bound protein 10

Down-regulated

ENSG00000084110

HAL

Histidine ammonia-lyase

Down-regulated

ENSG00000120694

HSPH1

Heat shock 105/110 kDa protein 1

Up-regulated

ENSG00000140443

IGF1R

Insulin-like growth factor 1 receptor

Down-regulated

ENSG00000197081

IGF2R

Insulin-like growth factor 2 receptor

Down-regulated

ENSG00000115604

IL18R1

Interleukin 18 receptor 1

Down-regulated

ENSG00000115594

IL1R1

Interleukin 1 receptor, type I

Down-regulated

ENSG00000115590

IL1R2

Interleukin 1 receptor, type II

Down-regulated

ENSG00000109452

INPP4B

Inositol polyphosphate-4-phosphatase, type II, 105 kDa

Up-regulated

ENSG00000102445

KIAA0226L

KIAA0226-like

Down-regulated

ENSG00000137261

KIAA0319

KIAA0319

Down-regulated

ENSG00000110318

KIAA1377

KIAA1377

Up-regulated

ENSG00000054523

KIF1B

Kinesin family member 1B

Down-regulated

ENSG00000138182

KIF20B

Kinesin family member 20B

Up-regulated

ENSG00000139116

KIF21A

Kinesin family member 21A

Up-regulated

ENSG00000068796

KIF2A

Kinesin heavy chain member 2A

Up-regulated

ENSG00000184445

KNTC1

Kinetochore associated 1

Up-regulated

ENSG00000126777

KTN1

Kinectin 1 (kinesin receptor)

Up-regulated

ENSG00000123384

LRP1

Low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor)

Down-regulated

ENSG00000186205

MARC1

Mitochondrial amidoxime reducing component 1

Down-regulated

ENSG00000257335

MGAM

Maltase-glucoamylase (alpha-glucosidase)

Down-regulated

ENSG00000171843

MLLT3

Myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3

Up-regulated

ENSG00000196549

MME

Membrane metallo-endopeptidase

Down-regulated

ENSG00000100985

MMP9

Matrix metallopeptidase 9 (gelatinase B, 92 kDa gelatinase, 92 kDa type IV collagenase)

Down-regulated

ENSG00000051825

MPHOSPH9

M-phase phosphoprotein 9

Up-regulated

ENSG00000138119

MYOF

Myoferlin

Up-regulated

ENSG00000049759

NEDD4L

Neural precursor cell expressed, developmentally down-regulated 4-like

Up-regulated

ENSG00000184613

NELL2

NEL-like 2 (chicken)

Up-regulated

ENSG00000173145

NOC3L

Nucleolar complex associated 3 homolog (S. cerevisiae)

Up-regulated

ENSG00000179299

NSUN7

NOL1/NOP2/Sun domain family, member 7

Down-regulated

ENSG00000111581

NUP107

Nucleoporin 107 kDa

Up-regulated

ENSG00000159339

PADI4

Peptidyl arginine deiminase, type IV

Down-regulated

ENSG00000123836

PFKFB2

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2

Down-regulated

ENSG00000075651

PLD1

Phospholipase D1, phosphatidylcholine-specific

Down-regulated

ENSG00000101868

POLA1

Polymerase (DNA directed), alpha 1

Up-regulated

ENSG00000080839

RBL1

Retinoblastoma-like 1 (p107)

Up-regulated

ENSG00000257743

RP11-1220K2.2

Putative inactive maltase-glucoamylase-like protein LOC93432

Down-regulated

ENSG00000226891

RP11-182I10.3

Uncharacterized LOC101927084

Down-regulated

ENSG00000258476

RP11-76E17.3

NA

Down-regulated

ENSG00000140386

SCAPER

S phase cyclin A-associated protein in the ER

Up-regulated

ENSG00000018280

SLC11A1

Solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1

Down-regulated

ENSG00000140090

SLC24A4

Solute carrier family 24 (sodium/potassium/calcium exchanger), member 4

Down-regulated

ENSG00000112053

SLC26A8

Solute carrier family 26, member 8

Down-regulated

ENSG00000157800

SLC37A3

Solute carrier family 37 (glycerol-3-phosphate transporter), member 3

Down-regulated

ENSG00000136824

SMC2

Structural maintenance of chromosomes 2

Up-regulated

ENSG00000163029

SMC6

Structural maintenance of chromosomes 6

Up-regulated

ENSG00000009694

TENM1

Teneurin transmembrane protein 1

Down-regulated

ENSG00000169902

TPST1

Tyrosylprotein sulfotransferase 1

Down-regulated

ENSG00000198677

TTC37

Tetratricopeptide repeat domain 37

Up-regulated

ENSG00000155657

TTN

Titin

Up-regulated

ENSG00000120800

UTP20

UTP20, small subunit (SSU) processome component, homolog (yeast)

Up-regulated

ENSG00000197969

VPS13A

Vacuolar protein sorting 13 homolog A (S. cerevisiae)

Up-regulated

ENSG00000163625

WDFY3

WD repeat and FYVE domain containing 3

Down-regulated

ENSG00000213799

ZNF845

Zinc finger protein 845

Up-regulated

ENSG00000167232

ZNF91

Zinc finger protein 91

Up-regulated