Fig. 2
Regional association plot for all significant ZFHX3 SNPs and response to AF ablation. The plot was created using GWAS association data that served as the input for gene-based testing. The x-axis represents the distribution of SNPs across ZFHX3 while the y-axis represents the −log10 of the P-value of each SNP in the gene. The colors indicate the r 2 between the SNP with the lowest P-value and all the other SNPs. The light blue trace indicates recombination hotspots